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INGREDIENT DICTIONARY

Pentylene Glycol (USP)

INCI: Pentylene Glycol | CAS #: 5343-92-0
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A multifunctional cosmetic ingredient used as a humectant, solvent, and formulation support component.

 

What is Pentylene Glycol (USP) & why is it used?

Pentylene glycol functions as both a humectant and solvent, helping attract water while improving the distribution of ingredients within a formulation.

It is often used alongside glycerin to balance hydration with improved sensory feel and can contribute to preservation strategies by supporting antimicrobial performance.

QUALITY MATTERS

Why specification quality matters

Pentylene Glycol is supplied as a high-purity, colourless liquid with consistent performance across formulations.

 This material is fermentation-derived and meets cosmetic-grade specifications, supporting predictable behaviour in formulation systems.   

Solubility Water soluble
Primary function Humectant
Use level 1.0–5.0%

Behaviour in formulations

Pentylene Glycol contributes to moisture retention while improving the dispersion and performance of other ingredients.

It can also enhance the overall sensory profile of formulations, helping reduce tackiness when used alongside other humectants.

Sensory notes

Pentylene glycol contributes a lightweight, smooth skin feel with lower perceived tack than glycerine at comparable use levels. It is commonly used to balance humectant systems, improving slip and overall sensory profile in both leave-on and rinse-off formulations. Sensory outcome is formulation-dependent; bench testing is recommended.

Formulation considerations

PROCESSING

Add to the water phase with mixing until fully uniform. Suitable for cold-process and heated systems.

Pentylene glycol integrates easily into most formulations and does not require pre-dissolving.

COMPATIBILITY
  • Compatible with most cosmetic ingredients and preservative systems
  • Often paired with glycerin, propanediol, or sodium PCA in humectant systemsS
  • Supports preservative efficacy in many formulations
pH
Stable across typical cosmetic pH ranges (approx. 4–8).
FORMULATION EXAMPLES
  • Hydrating toner (2–4%)
  • Barrier-support serum (2–5%)
  • Lightweight lotion (1–3%)
  • Preservative-support system (2–4%)

Use level considerations

Recommended range 1.0–5.0%
Suggested starting level 2–3% for most cosmetic formulations%

At typical use levels (1–5%), pentylene glycol provides effective hydration with a lighter, less sticky finish than glycerin.

At higher concentrations, it can influence viscosity and preservative performance, so balancing with other humectants and rheology modifiers is recommended.

Formulation summary

Pentylene Glycol functions as both a humectant and solvent within formulations.  

It is commonly used to improve ingredient solubility, support preservative systems, and enhance overall formulation balance. It integrates easily into water-based systems and can be used across a wide range of product types.

Quality notes

Pentylene Glycol is supplied as a high-purity, colourless liquid with consistent performance across formulations.

 This material is fermentation-derived and meets cosmetic-grade specifications, supporting predictable behaviour in formulation systems.