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INGREDIENT DICTIONARY
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D-Panthenol (Pro-Vitamin B5) - Cosmetic Grade

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INCI: Panthenol / CAS #: 81-13-0

Panthenol (Pro-Vitamin B5) is a water-soluble cosmetic ingredient used in formulations to support hydration, improve skin feel, and contribute to barrier function. It is widely used across skin and hair care systems due to its compatibility and consistent performance.

It is typically supplied as a viscous liquid and integrates easily into a wide range of formulation types.

Key benefits

  • Supports barrier function and skin conditioning
  • Improves hydration and moisture retention
  • Enhances formulation feel and softness
  • Compatible across skin and hair formulations

Behaviour in formulations

Panthenol is compatible with cold-process and heated systems, including gels, emulsions, and surfactant-based formulations. It is typically added to the water phase and mixes readily under standard processing conditions.

It performs well across both skin and hair formulations and integrates easily with common formulation systems.

Add to the water phase with mixing until uniform. Suitable for cold-process and heated systems.

Use level considerations

Use Rate (Min): 1.0
Use Rate (Max): 5.0

  • Leave-on: 1–5%
  • Rinse-off: 1–2%
  • Common in both skin and hair formulations

Starter Use Rate: 2-3% for most cosmetic formulations

Panthenol is typically used at 1–5% in leave-on formulations, where it supports hydration and conditioning effects. Lower levels (1–2%) are commonly used in rinse-off systems.

At higher levels, it may increase viscosity slightly or contribute to a heavier skin feel, so balancing with other humectants is recommended.

Formulation summary

  • Water-soluble active and humectant
  • Supports hydration and improves formulation feel
  • Suitable for gels, emulsions, and surfactant systems
  • Commonly used in barrier-support systems

Quality notes

Our panthenol is a cosmetic-grade ingredient supplied as a high-purity solution with a verified assay of 85.2% and low water content (0.13%), supporting stability and consistent formulation performance. COA-backed specifications confirm compliance with USP standards and batch-to-batch reliability.

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